Enlimomab
Based on 1 Customer Validation
Enlimomab (BI-RR 0001), a murine IgG2a monoclonal antibody to the human ICAM-1, inhibits leukocyte adhesion to the vascular endothelium, thereby decreasing leukocyte extravasation and inflammatory tissue injury. Enlimomab has anti-inflammatory effects, and can be used for stroke research .
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Pureté: 95.00%
- CAS No.: 142864-19-5
- Masse moléculaire:147.1 kDa
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Mouse IgG2a kappa
Human
ICAM1/CD54
In whole blood, Enlimomab activates resting neutrophils in a complement-dependent manner[1] .
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
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IgG2a-nd
ELISA, FACS, Functional assay
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Flow Cytometry analysis of Raji cells labelling ICAM1/CD54 (red) with Enlimomab (anti-ICAM1/CD54) (HY-P99336). Goat Anti-Human IgG (Alexa Fluor 488) (HY-P83776) at a dilution of 1/1000 was used as the secondary antibody. Blue-Mouse IgG2a kappa (HY-P99978). Black-Unlabelled control, cells without incubation with primary antibody.
Chemical Information
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CAS No. 142864-19-5
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Appearance Liquid
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Masse moléculaire 147.1 kDa
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Color Colorless to light yellow
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SMILES
[Enlimomab]
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Synonyms
BI-RR 0001; Anti-Human IL6 Recombinant Antibody
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Livraison
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
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Fiche technique (256 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Inhibitory Antibodies User Guide (603 KB)
Références
[1]. J Vuorte, et al. Anti-ICAM-1 monoclonal antibody R6.5 (Enlimomab) promotes activation of neutrophils in whole blood. J Immunol. 1999 Feb 15;162(4):2353-7. [Content Brief]
[2]. [2]Gregory J del Zoppo. Acute anti-inflammatory approaches to ischemic stroke. Ann N Y Acad Sci. 2010 Oct;1207:143-8. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Enlimomab Related Classifications
HY-P99336 Related Classifications
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