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Cat. No.: HY-146232

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F 13714

(Synonyms: F 14679)

F 13714 (F 14679) is a prototypical 5-HT_1A agonist with a pK_i of 10.23. F 13714 induces large Ca²⁺ responses.

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CAS No.: 208109-38-0
Formule: C₂₁H₂₅ClF₂N₄O
Masse moléculaire:422.90

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

F 13714 Chemical Structure

CAS No.: 208109-38-0

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Description

F 13714 (F 14679) is a prototypical 5-HT_1A agonist with a pK_i of 10.23. F 13714 induces large Ca²⁺ responses^[1].

IC₅₀ & Target

5-HT_1A Receptor

10.23 (pKi)

5-HT_1B Receptor

5.12 (pIC₅₀)

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Chemical Information

CAS No. 208109-38-0
Masse moléculaire 422.90
Formule C₂₁H₂₅ClF₂N₄O
SMILES

O=C(C1=CC(Cl)=C(F)C=C1)N2CCC(CNCC3=CC=C(C)C(NC)=N3)(F)CC2
Synonyms

F 14679
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Pauwels PJ, et al. Ca2+ responses in Chinese hamster ovary-K1 cells demonstrate an atypical pattern of ligand-induced 5-HT1A receptor activation. J Pharmacol Exp Ther. 2003 Nov;307(2):608-14. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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F 13714

Voir tous les produits spécifiques à Isoform 5-HT Receptor

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

F 13714 Related Classifications

HY-146232 Related Classifications