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Cat. No.: HY-164479

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GA001

GA001 is a potent G9a antagonist, with an IC₅₀ of 1.32 μM. GA001 induces autophagy and apoptosis that can be used for the breast cancer.

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CAS No.: 2097880-27-6
Formule: C₂₉H₂₄BrN₃O
Masse moléculaire:510.42

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

GA001 Chemical Structure

CAS No.: 2097880-27-6

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

GA001 is a potent G9a antagonist, with an IC₅₀ of 1.32 μM. GA001 induces autophagy and apoptosis that can be used for the breast cancer^[1].

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Chemical Information

CAS No. 2097880-27-6
Masse moléculaire 510.42
Formule C₂₉H₂₄BrN₃O
SMILES

O=C(C1=CC(Br)=CC=C1)NC2=CC=C3C(N=C(N3CCCC4=CC=CC=C4)C5=CC=CC=C5)=C2
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Zhang J, et al. Synthesis and biological evaluation of benzimidazole derivatives as the G9a Histone Methyltransferase inhibitors that induce autophagy and apoptosis of breast cancer cells. Bioorg Chem. 2017 Jun;72:168-181. [Content Brief]

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Calculateur de molarité

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Molecular Weight Molecular Weight

Calculateur de dilution

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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GA001

Voir tous les produits spécifiques à Isoform Histone Methyltransferase

Activité biologique

Description

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

GA001 Related Classifications

HY-164479 Related Classifications

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Keywords

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