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Cat. No.: HY-124482

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Mesembrenol

Mesembrenol is an alkaloid inhibitor of serotonin transporters and PDE4. Mesembrenol also inhibits glutamatergic AMPA receptors and can be used in research on mild to moderate depression.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

CAS No.: 25516-15-8
Formule: C₁₇H₂₃NO₃
Masse moléculaire:289.37

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (288 KB)

Mesembrenol Chemical Structure

CAS No.: 25516-15-8

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Chemical Information
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Description

Mesembrenol is an alkaloid inhibitor of serotonin transporters and PDE4. Mesembrenol also inhibits glutamatergic AMPA receptors and can be used in research on mild to moderate depression^[1].

IC₅₀ & Target

^[2]

PDE4

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Chemical Information

CAS No. 25516-15-8
Masse moléculaire 289.37
Formule C₁₇H₂₃NO₃
SMILES

O[C@@H]1C=C[C@]2(CCN([C@]2(C1)[H])C)C3=CC=C(C(OC)=C3)OC
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (288 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Alan Harvey et al. Use of pharmaceutical compositions containing mesembrenone. US8552051B2. 2010-03-16.

[2]. Gericke J et al. Sceletium tortuosum-derived mesembrine significantly contributes to the anxiolytic effect of Zembrin®, but its anti-depressant effect may require synergy of multiple plant constituents[J]. Journal of Ethnopharmacology, 2024, 319: 117113.

[3]. Dimpfel W et al. Effect of Zembrin® and four of its alkaloid constituents on electric excitability of the rat hippocampus[J]. Journal of ethnopharmacology, 2018, 223: 135-141.

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Chemical Information
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Mesembrenol

Voir tous les produits spécifiques à Isoform Phosphodiesterase (PDE)

Voir tous les produits spécifiques à Isoform iGluR

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