Methacycline
Based on 2 publication(s) in Google Scholar
Methacycline is a tetracycline antibiotic that inhibits bacterial protein synthesis. Methacycline is a potent inhibitor of epithelial-to-mesenchymal transition (EMT). Methacycline blocks EMT in vitro and inhibits fibrogenesis in vivo without directly affecting TGF-β1 Smad signaling. Methacycline is an antimicrobial agent with potential for use in pulmonary fibrosis research.
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- CAS No.: 914-00-1
- Formule: C22H22N2O8
- Masse moléculaire:442.42
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications Citing Use of MedChemExpress (MCE) Methacycline
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Activité biologique
Chemical Information
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CAS No. 914-00-1
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Masse moléculaire 442.42
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Formule C22H22N2O8
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SMILES
O[C@]12[C@]([C@H]([C@@]3([H])C(C(C4=C(O)C=CC=C4C3=C)=O)=C2O)O)([H])[C@@H](C(O)=C(C1=O)C(N)=O)N(C)C
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (2)
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Journal Impact Factor
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Most Recent
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EBioMedicine
A novel inhibitor of monooxygenase reversed the activity of tetracyclines against tet(X3)/tet(X4)-positive bacteria. [Abstract]2022 Apr;78:103943. PMID: 35306337 -
SLAS Discov
2020 Sep;25(8):895-905. PMID: 32567455
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)