ML165
ML165 (RUC-2) is an aIIbb3 receptor antagonist. ML165 has orthosteric inhibition effect at the RGD binding domain. ML165 inhibits platelet adhesion to fibrinogen, and inhibits platelet aggregation (IC50: 96 nM).
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- CAS No.: 1355454-05-5
- Formule: C17H19N7O2S
- Masse moléculaire:385.44
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
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- Références
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Help & FAQs
Activité biologique
Description
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Platelet | IC50 |
0.096 μM
Compound: 2, RUC-2, ML165
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Antiplatelet activity in platelet (unknown origin) assessed as inhibition of platelet aggregation
Antiplatelet activity in platelet (unknown origin) assessed as inhibition of platelet aggregation
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[PMID: 24461295] |
Chemical Information
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CAS No. 1355454-05-5
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Masse moléculaire 385.44
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Formule C17H19N7O2S
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SMILES
O=C(NC1=CC=CC(C(S2)=NN(C2=NC(N3CCNCC3)=C4)C4=O)=C1)CN
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Synonyms
RUC-2
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ML165 Related Classifications
HY-120694 Related Classifications
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