Penipanoid C
Penipanoid C (Compound 9) is a BRD4 inhibitor. Penipanoid C can be isolated from marine sediment-derived fungus Penicillium paneum SD-44. Penipanoid C has anti-inflammatory activity and cytotoxic activity against the SMMC-7721 cells. Penipanoid C can be used for inflammatory diseases research.
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- CAS No.: 1442381-95-4
- Formule: C15H10N2O3
- Masse moléculaire:266.25
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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BRD4 |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | IC50 |
>50 μM
Compound: 3a
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Cytotoxicity against human HepG2 cells assessed as inhibition of proliferation incubated for 72 hrs by MTT assay
Cytotoxicity against human HepG2 cells assessed as inhibition of proliferation incubated for 72 hrs by MTT assay
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[PMID: 34237623] |
Chemical Information
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CAS No. 1442381-95-4
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Masse moléculaire 266.25
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Formule C15H10N2O3
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SMILES
O=C1N=C(C(C2=CC=C(C=C2)O)=O)NC3=C1C=CC=C3
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Structure Classification
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Initial Source
Penicillium oxalicum
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Chen S, et al. Marine natural product-inspired discovery of novel BRD4 inhibitors with anti-inflammatory activity. Eur J Med Chem. 2025 Feb 15;284:117193. [Content Brief]
[2]. Li CS, et al. Triazole and dihydroimidazole alkaloids from the marine sediment-derived fungus Penicillium paneum SD-44. J Nat Prod. 2011 May 27;74(5):1331-4. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Penipanoid C Related Classifications
HY-N16067 Related Classifications
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