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Cat. No.: HY-142953

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UNC6349 (Ket2)

UNC6349 (Ket2), a diethyllysine (Ket2)-containing ligand, binds to wild-type CBX5, with a K_D of 3.2 μM.

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Formule: C₄₁H₅₇N₇O₁₁
Masse moléculaire:823.93

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (257 KB)

UNC6349 (Ket2) Chemical Structure

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

UNC6349 (Ket2), a diethyllysine (Ket2)-containing ligand, binds to wild-type CBX5, with a K_D of 3.2 μM^[1].

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Chemical Information

Masse moléculaire 823.93
Formule C₄₁H₅₇N₇O₁₁
SMILES

O=C(C1=COC=C1)NC([C@@H](O)C2=CC=CC=C2)C(N[C@@H](C)C(N[C@@H](CC3=CC=C(OC)C(OC)=C3)C(N[C@H](C(N[C@@H](CO)C(N)=O)=O)CCCCN(CC)CC)=O)=O)=O
Sequence

3-Furoic acid-3-Phenyl-L-Serine -Ala-Phe(3,4-Dimethoxy)-Lys(Et)2-Ser
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (257 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Kean KM, et al. Systematic Variation of Both the Aromatic Cage and Dialkyllysine via GCE-SAR Reveal Mechanistic Insights in CBX5 Reader Protein Binding. J Med Chem. 2022;65(3):2646-2655. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

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Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Activité biologique
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Chemical Information
Pureté et documentation
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UNC6349 (Ket2)

Voir tous les produits spécifiques à Isoform Epigenetic Reader Domain

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

UNC6349 (Ket2) Related Classifications

HY-142953 Related Classifications