CDK-IN-20
CDK-IN-20 is a selective CDK2 inhibitor with an IC50 value of <10 nM. CDK-IN-20 can be used for cancer research.
For research use only. We do not sell to patients.
- CAS No.: 2776187-63-2
- Formula: C16H17F3N4O5S
- Molecular Weight:434.39
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
CDK-IN-20 (Compound E7) exhibits moderate inhibitory activity against CDK1, CDK4, and CDK6, with IC50 values ranging from 100 nM to 1 μM; it shows extremely weak inhibitory activity against CDK7 and CDK9, with IC50 > 1 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2776187-63-2
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Molecular Weight 434.39
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Formula C16H17F3N4O5S
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SMILES
FC(F)(F)C(C(O[C@H]1[C@H](COCC1)O)=N2)=CN=C2NC3=CC=C(C=C3)S(N)(=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)