A63162
A63162 is a specific 5-lipoxygenase (5-LOX) inhibitor. A63162 inhibits mitogen (PHA)-induced horse mononuclear cell (BMC) proliferation and inhibits Calcimycin (HY-N6687)-induced leukotriene LTB4 synthesis at the same concentration. A63162 can be used in the study of chronic obstructive pulmonary disease, arthritis and inflammatory bowel disease.
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- CAS. Nr.: 111525-11-2
- Formel: C17H19NO3
- Molecular Weight:285.34
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Biologische Aktivität
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| RBL-1 | IC50 |
0.37 μM
Compound: 4b
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In vitro inhibition of 5-lipoxygenase in RBL-1 cells
In vitro inhibition of 5-lipoxygenase in RBL-1 cells
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[PMID: 3336029] |
Chemical Information
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CAS. Nr. 111525-11-2
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Molecular Weight 285.34
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Formel C17H19NO3
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SMILES
CC(N(C(C)C1=CC=C(C=C1)OCC2=CC=CC=C2)O)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
A63162 Related Classifications
HY-118848 Related Classifications
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