F0911-7667
F0911-7667 is a SIRT1 activator that induces autophagic cell death in U87MG and T98G cells by activating the AMPK-mTOR-ULK complex. CWR tripeptide was also identified as a SIRT1 activator that reduced p53 acetylation in IMR32 neuroblastoma cells and protected cells from cell death induced by Aβ fragments.
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- CAS. Nr.: 361198-09-6
- Formel: C26H19ClN4O3S2
- Molecular Weight:535.04
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
SIRT1[1]
Chemical Information
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CAS. Nr. 361198-09-6
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Molecular Weight 535.04
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Formel C26H19ClN4O3S2
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SMILES
O=C1N(C2=NC3=CC=CC=C3S2)N=C(CSC4=CC=C(Cl)C=C4)/C1=C\NCC5=CC=C(OCO6)C6=C5
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)