HDAC6-IN-59
HDAC6-IN-59 (Compound 38k) is a highly selective histone deacetylase 6 (HDAC6) inhibitor (IC50=3.12 nM, with 352-fold selectivity over HDAC1). HDAC6-IN-59 is promising for research of esophageal cancer.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 2998932-98-0
- Formel: C22H18ClN5O2
- Molecular Weight:419.86
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Beschreibung
IC50 & Target
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HDAC1 |
HDAC6 3.12 nM (IC50) |
Chemical Information
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CAS. Nr. 2998932-98-0
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Molecular Weight 419.86
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Formel C22H18ClN5O2
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SMILES
O=C(C1=CC=C(CNC2=NC(C3=CC=C(C=C3)Cl)=NN2C4=CC=CC=C4)C=C1)NO
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Protokoll
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)