country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Art. -Nr.: HY-161707

Copy Link Print Information

MMP2-IN-4

MMP2-IN-4 (compound 3h) is a potent MMP2 inhibitor. MMP2-IN-4 inhibits MMP2, MMP9 and MMP12 with IC₅₀s of 266.74, 402.75 and 1237.39 nM, respectively.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

CAS. Nr.: 92535-43-8
Formel: C₁₉H₂₂N₂O₅S
Molecular Weight:390.45

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

MMP2-IN-4 Chemical Structure

CAS. Nr.: 92535-43-8

Größe

Preis

Verfügbarkeit

Menge

Amount: USD 0.00

* Bitte wählen Sie Menge, bevor Sie Artikel hinzufügen.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- Cellular Effect
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

MMP2-IN-4 (compound 3h) is a potent MMP2 inhibitor. MMP2-IN-4 inhibits MMP2, MMP9 and MMP12 with IC₅₀s of 266.74, 402.75 and 1237.39 nM, respectively^[1].

Alle MMP Isoform-spezifische Produkte anzeigen :

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	3.57 μM Compound: 3h'	Antiproliferative activity against human A549 cells incubated for 72 hrs by MTT assay Antiproliferative activity against human A549 cells incubated for 72 hrs by MTT assay	[PMID: 38843586]
ACHN	IC₅₀	17.15 μM Compound: 3h'	Antiproliferative activity against human ACHN cells incubated for 72 hrs by MTT assay Antiproliferative activity against human ACHN cells incubated for 72 hrs by MTT assay	[PMID: 38843586]
HEK293	IC₅₀	292.73 μM Compound: 3h'	Cytotoxicity against HEK293 cells incubated for 72 hrs by MTT assay Cytotoxicity against HEK293 cells incubated for 72 hrs by MTT assay	[PMID: 38843586]
HT-1080	IC₅₀	19.67 μM Compound: 3h'	Antiproliferative activity against human HT-1080 cells incubated for 72 hrs by MTT assay Antiproliferative activity against human HT-1080 cells incubated for 72 hrs by MTT assay	[PMID: 38843586]
K562	IC₅₀	1.99 μM Compound: 3h'	Antiproliferative activity against human K562 cells incubated for 72 hrs by PrestoBlue assay Antiproliferative activity against human K562 cells incubated for 72 hrs by PrestoBlue assay	[PMID: 38843586]
U-87MG ATCC	IC₅₀	17.53 μM Compound: 3h'	Antiproliferative activity against human U-87 MG cells incubated for 72 hrs by MTT assay Antiproliferative activity against human U-87 MG cells incubated for 72 hrs by MTT assay	[PMID: 38843586]

Chemical Information

CAS. Nr. 92535-43-8
Molecular Weight 390.45
Formel C₁₉H₂₂N₂O₅S
SMILES

CC1=CC=C(S(N[C@@H](C(O)=O)CCC(NCC2=CC=CC=C2)=O)(=O)=O)C=C1
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Das S, et al. Derivatives of D(-) glutamine-based MMP-2 inhibitors as an effective remedy for the management of chronic myeloid leukemia-Part-I: Synthesis, biological screening and in silico binding interaction analysis. Eur J Med Chem. 2024 Aug 5;274:116563. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

Angebot einholen Auf Lager

Other size

Angebot einholen

Amount: USD 0.00

Biologische Aktivität
- Beschreibung
Chemical Information
Reinheit & Dokumentation
Verweise

Produktname:
Art. -Nr.:
Menge:
MCE Japan Authorized Agent:

Produktname:
CAS. Nr.:
Species:
Reinheit:
Menge:

MMP2-IN-4

Alle MMP Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

MMP2-IN-4 Related Classifications

HY-161707 Related Classifications