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Sarilumab

(Synonyms: Anti-Human IL6Rα, Human Antibody)
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Sarilumab is a monoclonal antibody targeting IL6 that binds to IL6R and blocks the binding of IL6, thereby inhibiting the activation of the downstream STAT3 phosphorylation signaling pathway. In tumor cells with active IL6/STAT3 signaling pathways, Sarilumab induces Apoptosis and inhibits cell growth. Sarilumab is applicable to research related to prostate cancer, lung cancer and rheumatoid arthritis.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

  • Reinheit: 99.36%
  • CAS. Nr.: 1189541-98-7
  • Molecular Weight:144.12 kDa
  • Speicherung:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Sarilumab
  • Experimental Validation Results for Sarilumab
  • Sarilumab Chemical Structure
    Sarilumab Chemical Structure
CAS. Nr.: 1189541-98-7
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Sarilumab Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Finden Sie Ihren Händler vor Ort Your local distributor: Hycultec GmbHHycultec
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Top Publications Citing

Use of MCE Products

Alle Interleukin Related Isoform-spezifische Produkte anzeigen

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Alle STAT Isoform-spezifische Produkte anzeigen

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Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Immobilized IL-6R alpha Protein, Human can bind Sarilumab. The EC50 for this effect is 34.98 ng/mL.

  • Sarilumab Chemical Structure
    1/16
  • Sarilumab
  • Immobilized IL-6R alpha Protein, Human can bind Sarilumab. The EC50 for this effect is 34.98 ng/mL.