Stephanine
Based on 1 publication(s) in Google Scholar
Stephanine ((-)-Stephanine) is an isoquinoline aporphine-type alkaloid. Stephanine induce apoptosis through the reverse of mitotic exit. Stephanine exhibits Antiplasmodial activity. Stephanine can be used for the research of stomach pain, abdominal pain, arthritis and cancer.
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- CAS. Nr.: 517-63-5
- Formel: C19H19NO3
- Molecular Weight:309.36
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Publications Citing Use of MedChemExpress (MCE) Stephanine
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Biologische Aktivität
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Cell Line
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Type | Value | Description | References |
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| BV-2 | IC50 |
20.26 μM
Compound: 11
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Inhibition of NO production in LPS-induced mouse BV-2 cells incubated for 24 hrs by Griess reagent based microplate reader analysis
Inhibition of NO production in LPS-induced mouse BV-2 cells incubated for 24 hrs by Griess reagent based microplate reader analysis
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[PMID: 37172474] |
Chemical Information
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CAS. Nr. 517-63-5
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Molecular Weight 309.36
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Formel C19H19NO3
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SMILES
CN1CCC(C2=C3C4=CC=CC(OC)=C4C[C@@]12[H])=CC5=C3OCO5
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Synonyms
(-)-Stephanine; l-Stephanine
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Structure Classification
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Initial Source
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
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Vet Microbiol
Antiviral activity of Stephania japonica extract against porcine epidemic diarrhea virus infection. [Abstract]2025 Sep:308:110647. PMID: 40706130
Reinheit & Dokumentation
Verweise
[1]. Cui L, et, al. The anti-inflammatory and analgesic activities of 2Br-Crebanine and Stephanine from Stephania yunnanenses H. S.Lo. Front Pharmacol. 2023 Jan 4;13:1092583. [Content Brief]
[2]. Le PM, et, al. Stephanine from Stephania venosa (Blume) Spreng Showed Effective Antiplasmodial and Anticancer Activities, the Latter by Inducing Apoptosis through the Reverse of Mitotic Exit. Phytother Res. 2017 Sep;31(9):1357-1368. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Stephanine Related Classifications
HY-N1219 Related Classifications
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