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Art. -Nr.: HY-182535

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Tuberactinomycin-O

Tuberactinomycin-O is a peptide antibiotic belonging to the tuberactinomycin family. Tuberactinomycin-O inhibits the growth of various bacteria, including Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and Mycobacterium ATCC 607. Tuberactinomycin-O exhibits acute toxicity in male mice when administered intravenously. Tuberactinomycin-O can be used in the research of tuberculosis.

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CAS. Nr.: 33137-73-4
Formel: C₂₅H₄₃N₁₃O₉
Molecular Weight:669.69

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Tuberactinomycin-O Chemical Structure

CAS. Nr.: 33137-73-4

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Biologische Aktivität
- Beschreibung
- In Vitro
- In Vivo
Chemical Information
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Bioz

Biologische Aktivität

Beschreibung

Alle Antibiotic Isoform-spezifische Produkte anzeigen :

In Vitro

Tuberactinomycin-O (24 h) inhibits the growth of multiple bacterial strains in vitro, with the highest potency against Bacillus subtilis PCI 219 (MIC 3.2 mcg/mL) and Mycobacterium ATCC 607 (MIC 6.3 mcg/mL), and the lowest potency against Staphylococcus aureus FDA 209 P and Sarcina lutea ATCC 1001 (MIC 100 mcg/mL)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Tuberactinomycin-O (370 mg/kg; i.v.; single dose) exhibits an acute intravenous LD₅₀ of 370 mg/kg in male mice^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

Mice (male)^[1]
Dosage:

/
Administration:

i.v.; single dose
Result:

Determined an acute median lethal dose (LD₅₀) of 370 mg/kg.

Chemical Information

CAS. Nr. 33137-73-4
Molecular Weight 669.69
Formel C₂₅H₄₃N₁₃O₉
SMILES

O=C1[C@](NC(/C(NC([C@@H](NC([C@@H](NC([C@H](CN1)NC(C[C@@H](N)CCCN)=O)=O)CO)=O)CO)=O)=C/NC(N)=O)=O)([H])[C@]2([H])NC(N)=NCC2
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. IZUMI R, et al. Studies on tuberactinomycin. III Isolation and characterization of two minor components, tuberactinomycin B and tuberactinomycin O. The Journal of Antibiotics, 1972, 25(4): 201-207.

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Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biologische Aktivität
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Tuberactinomycin-O

Alle Antibiotic Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

Tuberactinomycin-O Related Classifications

HY-182535 Related Classifications