HTL-9936
HTL-9936 is a selective M1 muscarinic acetylcholine receptor (M1-mAChR) agonist. HTL-9936 is promising for research of neurodegenerative disorders (e.g., Alzheimer’s).
For research use only. We do not sell to patients.
- CAS No.: 1438242-59-1
- Formula: C20H35N3O3
- Molecular Weight:365.51
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 1438242-59-1
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Molecular Weight 365.51
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Formula C20H35N3O3
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SMILES
CC1(CCC1)NC(C2CCN([C@@H]3CCN(CCC3)C(OCC)=O)CC2)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Nguyen HTM, et al. Opportunities and challenges for the development of M1 muscarinic receptor positive allosteric modulators in the treatment for neurocognitive deficits. Br J Pharmacol. 2024 Jul;181(14):2114-2142. [Content Brief]
[2]. Brown AJH, et al. From structure to clinic: Design of a muscarinic M1 receptor agonist with potential to treatment of Alzheimer's disease. Cell. 2021 Nov 24;184(24):5886-5901.e22. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)