NYLTHRQ
NYLTHRQ is a peptide. NYLTHRQ specifically blocks the interaction between sVEGFR1-i13 and β1 integrin, and inhibits the activation of VEGFR1 and VEGFR2. NYLTHRQ inhibits cancer cell proliferation. NYLTHRQ can be used in the research of tumors such as lung squamous cell carcinoma.
For research use only. We do not sell to patients.
- CAS No.: 1004284-41-6
- Formula: C40H62N14O12
- Molecular Weight:931.01
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All VEGFR Isoforms
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Biological Activity
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VEGFR1 |
VEGFR2 |
NYLTHRQ (10 μg/mL; 72 h) specifically blocks the interaction between sVEGFR1-i13 and β1 integrin in MGH7 cells, inhibits VEGFR activation, and reduces cell proliferation activity[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:MGH7 squamous cell lung carcinoma (SQLC) cells
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Concentration:10 μg/mL
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Incubation Time:72 h
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Result:Prevented the activation of VEGFR1 (Tyr1213) and VEGFR2 (Tyr1214) proteins.
Blocked the increased cell proliferation induced by sVEGFR1-i13-containing conditioned supernatants.
Chemical Information
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CAS No. 1004284-41-6
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Molecular Weight 931.01
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Formula C40H62N14O12
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Sequence
Asn-Tyr-Leu-Thr-His-Arg-Gln
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Sequence Shortening
NYLTHRQ
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
NYLTHRQ Related Classifications
HY-P11649 Related Classifications
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