8-Bromo-AMP
Based on 1 publication(s) in Google Scholar
8-Bromo-AMP (8-Bromoadenosine 5'-monophosphate) is a membrane permeable cAMP analogue. 8-Bromo-AMP can improve the ability of the heart to recover from ischemia and reperfusion by increasing the levels of ATP, ADP, and total adenine nucleotides.
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- Pureté: 98.78%
- CAS No.: 23567-96-6
- Formule: C10H13BrN5O7P
- Masse moléculaire:426.12
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Stockage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) 8-Bromo-AMP
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Activité biologique
Chemical Information
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CAS No. 23567-96-6
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Appearance Solid
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Masse moléculaire 426.12
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Formule C10H13BrN5O7P
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Color White to off-white
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SMILES
O=P(O)(OC[C@@H]1[C@H]([C@H]([C@H](N2C(Br)=NC3=C(N=CN=C32)N)O1)O)O)O
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Synonyms
8-Bromoadenosine 5'-monophosphate; 8-Bromoadenylic acid
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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Mil Med Res
2023 Dec 12;10(1):64. PMID: 38082365
Solvant et solubilité
H2O : 125 mg/mL (293.34 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (277 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instruction de manipulation (2659 KB)
Références
[1]. Jiang J, et, al. Evidences for involvement of endogenous cAMP in Arabidopsis defense responses to Verticillium toxins. Cell Res. 2005 Aug;15(8):585-92. [Content Brief]
[2]. Nakai T, et, al. Effects of adenine nucleotide analogues on myocardial dysfunction during reperfusion after ischemia in dogs. J Cardiovasc Pharmacol. 1996 Aug;28(2):264-70. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 2.3468 mL | 11.7338 mL | 23.4676 mL | 58.6689 mL |
| 5 mM | 0.4694 mL | 2.3468 mL | 4.6935 mL | 11.7338 mL | |
| 10 mM | 0.2347 mL | 1.1734 mL | 2.3468 mL | 5.8669 mL | |
| 15 mM | 0.1565 mL | 0.7823 mL | 1.5645 mL | 3.9113 mL | |
| 20 mM | 0.1173 mL | 0.5867 mL | 1.1734 mL | 2.9334 mL | |
| 25 mM | 0.0939 mL | 0.4694 mL | 0.9387 mL | 2.3468 mL | |
| 30 mM | 0.0782 mL | 0.3911 mL | 0.7823 mL | 1.9556 mL | |
| 40 mM | 0.0587 mL | 0.2933 mL | 0.5867 mL | 1.4667 mL | |
| 50 mM | 0.0469 mL | 0.2347 mL | 0.4694 mL | 1.1734 mL | |
| 60 mM | 0.0391 mL | 0.1956 mL | 0.3911 mL | 0.9778 mL | |
| 80 mM | 0.0293 mL | 0.1467 mL | 0.2933 mL | 0.7334 mL | |
| 100 mM | 0.0235 mL | 0.1173 mL | 0.2347 mL | 0.5867 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
8-Bromo-AMP Related Classifications
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