AP22408
AP22408 is a nonpeptide inhibitor against Src SH2 with an IC50 value of 0.3 μM. AP22408 inhibits rabbit osteoclast-mediated resorption of dentine, exhibits bone-targeting properties based on a hydroxyapatite adsorption assay and demonstrates in vivo antiresorptive activity in a parathyroid hormone-induced rat model. AP22408 is proming for rasearch of osteoporosis and other bone-related diseases such as Paget’s disease, osteolytic bone metastasis and hypercalcemia associated with malignancy.
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- CAS No.: 268741-43-1
- Formule: C30H41N3O10P2
- Masse moléculaire:665.61
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
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Activité biologique
Chemical Information
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CAS No. 268741-43-1
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Masse moléculaire 665.61
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Formule C30H41N3O10P2
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SMILES
O=C(N[C@H]1CCCCC2=CC(OCC3CCCCC3)=C(C(N)=O)C=C21)[C@@H](NC(C)=O)CC4=CC=C(P(O)(O)=O)C(P(O)(O)=O)=C4
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AP22408 Related Classifications
HY-125064 Related Classifications
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