CDK7-IN-5
CDK7-IN-5 is a CDK7 inhibitor with an IC50 value <100 nM. CDK7-IN-5 has anticancer effects. (WO2015154022A1 (Compound 104)).
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- CAS No.: 1817006-50-0
- Formule: C34H45N9O2
- Masse moléculaire:611.78
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Protocole
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
IC50 & Target
[1]|
CDK7 <100 nM (IC50) |
In Vitro
CDK7-IN-5 (Comp 104; 72 hours) inhibits the proliferation of A673 cells with an IC50 <500 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 1817006-50-0
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Masse moléculaire 611.78
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Formule C34H45N9O2
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SMILES
CC(C1=C2N(N=C1)C(NCC3=C(C=CC=C3)NCC4=CC=C(C=C4)NC(/C=C/CN(C)C)=O)=NC(OC5CCN(CC5)C)=N2)C
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocole
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CDK7-IN-5 Related Classifications
HY-139986 Related Classifications
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