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Cat. No.: HY-180184

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DLG-41nc

DLG-41nc is the negative control for DLG-41 (HY-180183). DLG-41nc shows no GAS41 YEATS domain inhibition (IC₅₀: >50 μM in AlphaLISA). DLG-41 has anticancer activity against NSCLC.

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Formule: C₃₁H₃₄N₆O₃S₂
Masse moléculaire:602.77

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

DLG-41nc Chemical Structure

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

DLG-41nc is the negative control for DLG-41 (HY-180183). DLG-41nc shows no GAS41 YEATS domain inhibition (IC₅₀: >50 μM in AlphaLISA). DLG-41 has anticancer activity against NSCLC^[1].

IC₅₀ & Target

IC₅₀: >50 μM (GAS41 YEATS) in AlphaLISA^[1]

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Chemical Information

Masse moléculaire 602.77
Formule C₃₁H₃₄N₆O₃S₂
SMILES

CC1(CN[C@@H](C1)C(NC2=NC=C(S2)C(N3CC(C4=NC=C(C5=C6C(C=CC=C6)=C(C=C5)CNC(CC)=O)S4)C3)=O)=O)C
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Listunov D, et al. Discovery and Development of a Small-Molecule Inhibitor Targeting the GAS41 YEATS Domain in Nonsmall Cell Lung Cancer. J Med Chem. 2025 Dec 11;68(23):25324-25351. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références

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DLG-41nc

Voir tous les produits spécifiques à Isoform Epigenetic Reader Domain

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

DLG-41nc Related Classifications

HY-180184 Related Classifications