DPP
DPP is a Platinum(IV) complex, bearing pterostilbene-derived axial ligand. DPP inhibit the JAK2-STAT3 pathway in breast cancer (BC) cells with antiproliferative activity, and activates caspase-3 and cleaved poly ADP-ribose polymerase to induces apoptosis. DPP promotes the maturation and antigen presentation of dendritic cells, and exhibits in vivo safety.
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- CAS No.: 2668267-47-6
- Formule: C36H40Cl2N2O10Pt
- Masse moléculaire:926.70
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 2668267-47-6
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Masse moléculaire 926.70
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Formule C36H40Cl2N2O10Pt
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SMILES
COC1=CC(OC)=CC(/C=C/C(C=C2)=CC=C2OCC([O-][Pt+4]([Cl-])([Cl-])([NH3])([NH3])[O-]C(COC(C=C3)=CC=C3/C=C/C4=CC(OC)=CC(OC)=C4)=O)=O)=C1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
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Fiche technique (264 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instruction de manipulation (2659 KB)
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)