Eremomycin
Based on 1 Customer Validation
Eremomycin (MM 45289) is a potent glycopeptide antibiotic closely related to Vancomycin (HY-B0671). Eremomycin shows antibacterial activity in Staphylococcus spp. and Bacillus subtilis ATCC6633, with the MIC values of 0.03-1.6 μg/mL.
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- Pureté: 95.87%
- CAS No.: 110865-90-2
- Formule: C73H89ClN10O26
- Masse moléculaire:1557.99
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Stockage:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Activité biologique
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CCRF-CEM | IC50 |
>500 μM
Compound: 5
|
Inhibitory concentration against proliferation of human T-lymphocytic (CEM) cells
Inhibitory concentration against proliferation of human T-lymphocytic (CEM) cells
|
[PMID: 12801238] |
| L1210 | IC50 |
>500 μM
Compound: 5
|
Inhibitory concentration of compound against proliferation of murine lukemia cells L1210 was determined
Inhibitory concentration of compound against proliferation of murine lukemia cells L1210 was determined
|
[PMID: 12801238] |
| MOLT-4 | IC50 |
>500 μM
Compound: 5
|
Inhibitory concentration of compound against proliferation of human T-lymphocytic cells MOLT-4/C8 was determined
Inhibitory concentration of compound against proliferation of human T-lymphocytic cells MOLT-4/C8 was determined
|
[PMID: 12801238] |
Chemical Information
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CAS No. 110865-90-2
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Appearance Solid
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Masse moléculaire 1557.99
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Formule C73H89ClN10O26
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Color White to off-white
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SMILES
C[C@@](N)([C@H]([C@@H](O1)C)O)C[C@@H]1O[C@@H]([C@]2([H])NC([C@](C3=CC=C(O)C(C4=C(O)C=C(O)C=C4[C@H](NC2=O)C(O)=O)=C3)([H])NC([C@]5([H])NC([C@@H](NC([C@@H]([C@@H](C6=CC=C(O7)C(Cl)=C6)O)NC([C@H](NC)CC(C)C)=O)=O)CC(N)=O)=O)=O)=O)C8=CC=C(C=C8)OC9=CC5=CC7=C9O[C@H]%10[C@@H]([C@H]([C@@H]([C@H](O%10)CO)O)O)O[C@H]%11C[C@](N)([C@H]([C@@H](O%11)C)O)C
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Synonyms
MM 45289; A 82846A
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Structure Classification
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Initial Source
Amycolatopsis orientalis
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvant et solubilité
H2O : 100 mg/mL (64.19 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (277 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 0.6419 mL | 3.2093 mL | 6.4185 mL | 16.0463 mL |
| 5 mM | 0.1284 mL | 0.6419 mL | 1.2837 mL | 3.2093 mL | |
| 10 mM | 0.0642 mL | 0.3209 mL | 0.6419 mL | 1.6046 mL | |
| 15 mM | 0.0428 mL | 0.2140 mL | 0.4279 mL | 1.0698 mL | |
| 20 mM | 0.0321 mL | 0.1605 mL | 0.3209 mL | 0.8023 mL | |
| 25 mM | 0.0257 mL | 0.1284 mL | 0.2567 mL | 0.6419 mL | |
| 30 mM | 0.0214 mL | 0.1070 mL | 0.2140 mL | 0.5349 mL | |
| 40 mM | 0.0160 mL | 0.0802 mL | 0.1605 mL | 0.4012 mL | |
| 50 mM | 0.0128 mL | 0.0642 mL | 0.1284 mL | 0.3209 mL | |
| 60 mM | 0.0107 mL | 0.0535 mL | 0.1070 mL | 0.2674 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.