country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-185345

Copy Link Print Information

GR119566X

GR119566X is a 5-HT₃ receptor ligand with a pK_i value of 8.80 against prufied 5-HT₃ receptor. GR119566X can be used for 5-HT₃ receptor purification.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

CAS No.: 237752-42-0
Formule: C₂₀H₂₄N₄O
Masse moléculaire:336.43

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

GR119566X Chemical Structure

CAS No.: 237752-42-0

Size

Prix

Stock

Quantité

Amount: USD 0.00

* Veuillez sélectionner la quantité avant d'ajouter des articles.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

GR119566X is a 5-HT₃ receptor ligand with a pK_i value of 8.80 against prufied 5-HT₃ receptor. GR119566X can be used for 5-HT₃ receptor purification^[1].

IC₅₀ & Target

5-HT₃ Receptor

Voir tous les produits spécifiques à Isoform 5-HT Receptor :

In Vitro

GR119566X (12.5 mg; 16 h) is successfully coupled to Aﬃ-Gel 15 to form an affinity resin that specifically retains solubilized 5-HT₃ receptors from porcine cerebral cortex, enabling receptor purification^[1].
GR119566X (60 min at 37°C) binds to membrane-bound, solubilized, and affinity-purified 5-HT₃ receptors from porcine cerebral cortex with consistent high affinity, as shown by pK_i values ranging from 8.21 to 8.80^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 237752-42-0
Masse moléculaire 336.43
Formule C₂₀H₂₄N₄O
SMILES

NCCCN1C(CCC(C2=O)CC3=C(N=CN3)C)=C2C4=C1C=CC=C4
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Fletcher S, et al. Purification of 5-hydroxytryptamine3 receptors from porcine brain. Br J Pharmacol. 1997 Oct;122(4):655-62. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

Obtenir un devis En stock

Amount: USD 0.00

Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureté et documentation
Références

Nom du produit:
Cat. No.:
Quantité:
MCE Japan Authorized Agent:

Nom du produit:
CAS No.:
Species:
Pureté:
Quantité:

GR119566X

High-Throughput Bioactive Compound Library

Voir tous les produits spécifiques à Isoform 5-HT Receptor

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

GR119566X Related Classifications

HY-185345 Related Classifications