HDAC8-IN-8
Based on 1 Customer Validation
HDAC8-IN-8 (15a) is an HDAC8 inhibitor, with IC50 values of 23.9 μM and 268.2 μM for hHDAC8 and smHDAC8 respectively. And for hHDAC1 and hHDAC6, the IC50 values are 12.1 μM and 2.9 μM respectively. HDAC8-IN-8 can be used in schistosomiasis-related research.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Pureté: 95.0%
- CAS No.: 1884231-52-0
- Formule: C15H15NO4
- Masse moléculaire:273.28
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Stockage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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hHDAC8 23.9 μM (IC50) |
smHDAC8 268.2 μM (IC50) |
hHDAC1 12.1 μM (IC50) |
hHDAC6 2.9 μM (IC50) |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| BE(2)-C | IC50 |
12.7 μM
Compound: 20a
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Cytotoxicity against human BE(2)-C cells assessed as reduction in cell viability by measuring metabolic activity after 72 hrs by WST-8 assay
Cytotoxicity against human BE(2)-C cells assessed as reduction in cell viability by measuring metabolic activity after 72 hrs by WST-8 assay
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[PMID: 29190092] |
HDAC8-IN-8 (15a) (50 μM, 24 h) results in 69.1% viability of HEK293 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1884231-52-0
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Appearance Solid
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Masse moléculaire 273.28
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Formule C15H15NO4
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Color White to off-white
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SMILES
O=C(C1=CC=C(C(OCC2=CC=CC=C2)=C1)OC)NO
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Pureté et documentation
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Fiche technique (267 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instruction de manipulation (2659 KB)
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
HDAC8-IN-8 Related Classifications
HY-124782 Related Classifications
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