HPO-DAEE

(Synonyms: 4-Hydroperoxy-2-decenoic acid ethyl ester)

HPO-DAEE (4-Hydroperoxy-2-decenoic acid ethyl ester) elicits nuclear accumulation of Nrf2 and activated antioxidant response element (ARE). HPO-DAEE induces antioxidant genes upregulation (eg: HO-1) through Nrf2-ARE signaling. HPO-DAEE induces reactive oxygen species generation. HPO-DAEE also inhibits histone deacetylase and upregulate expression of extracellular superoxide dismutase via histone acetylation. HPO-DAEE protects against 6-hydroxydopamine-induced cell death via activation of Nrf2-ARE and eIF2α-ATF4 pathways.

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  • CAS No.: 1895934-61-8
  • Formule: C12H22O4
  • Masse moléculaire:230.30
  • Stockage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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