IS4

IS4 is a selective CXCR4 competitive antagonist, with an IC50 of 0.65 nM in THP-1 cells and 38.75 nM in Jurkat cells. IS4 is stable in serum and non-cytotoxic. IS4 competitively binds to CXCR4 with CXCL12, thereby inhibiting CXCL12-induced intracellular Ca2+ release and cancer cell migration. IS4 can be used in the research on the prevention of metastasis of breast cancer, prostate cancer, leukemia, and other diseases.

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  • CAS No.: 3067986-23-3
  • Formule: C48H62N14O11S2
  • Masse moléculaire:1075.22
  • Stockage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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100 mg

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