LMD-902
LMD-902, a LMD-009 (HY-121885) analog, is a CCR8 agonist with an EC50 of 15 nM. LMD-902 has a superior binging capacity depending on key residues such as PheVI:16. LMD-902 can be used for inflammation diseases like bronchial asthma and central nervous system diseases like multiple sclerosis research.
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- CAS No.: 521979-59-9
- Formule: C28H34N2O6S
- Masse moléculaire:526.64
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
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CCR8 15 nM (EC50) |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| COS-7 | EC50 |
15 nM
Compound: 73; LMD-902
|
Antiproliferative activity against African green monkey COS7 cells assessed as inhibition of cell growth
Antiproliferative activity against African green monkey COS7 cells assessed as inhibition of cell growth
|
[PMID: 28165741] |
Chemical Information
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CAS No. 521979-59-9
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Masse moléculaire 526.64
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Formule C28H34N2O6S
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SMILES
O=S(NCC)(C1=CC=C(C=C1C2(CCN(CC2)CC3=CC(OC4=C(OC)C=CC=C4)=CC=C3)O)OC)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)