ML901
ML901 is an antimalarial agent with an IC50 value of 2 nM against the malaria parasite. ML901 specifically inhibits the tyrosine tRNA synthetase of the malaria parasite (PfYRS) through "receptor hijacking". ML901 exhibits full life-cycle killing activity in the malaria mouse model. ML901 can be used for studying malaria parasite infection.
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- CAS No.: 2226228-02-8
- Formule: C11H14F2N6O7S
- Masse moléculaire:412.33
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
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Activité biologique
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| NCI-H1650 | EC50 |
10.02 μM
Compound: 4
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Antiproliferative activity against human H1650 cells assessed as reduction in cell viability after 72 hrs by cell titer glow assay
Antiproliferative activity against human H1650 cells assessed as reduction in cell viability after 72 hrs by cell titer glow assay
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[PMID: 32912429] |
Chemical Information
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CAS No. 2226228-02-8
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Masse moléculaire 412.33
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Formule C11H14F2N6O7S
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SMILES
O[C@@H]1[C@H](O)[C@@H](COS(N)(=O)=O)O[C@H]1N2C3=NC=NC(N)=C3C(OC(F)F)=N2
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ML901 Related Classifications
HY-171215 Related Classifications
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