Cyclopropaneacetamide-Exatecan
Based on 1 Customer Validation
Cyclopropaneacetamide-Exatecan is an Exatecan (HY-13631) analogue and an ADC Cytotoxin. Cyclopropaneacetamide-Exatecan can be used to synthesize ADC molecules for cancer research.
For research use only. We do not sell to patients.
- Purity: 99.60%
- CAS No.: 2414254-36-5
- Formula: C29H28FN3O6
- Molecular Weight:533.55
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Storage:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
All Topoisomerase Isoforms
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Biological Activity
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Camptothecins |
Chemical Information
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CAS No. 2414254-36-5
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Appearance Solid
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Molecular Weight 533.55
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Formula C29H28FN3O6
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Color Off-white to yellow
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SMILES
O[C@@H](C1CC1)C(N[C@@H]2C3=C4C(C(N5C4)=CC([C@](O)(C(OC6)=O)CC)=C6C5=O)=NC7=CC(F)=C(C)C(CC2)=C73)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 100 mg/mL (187.42 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (280 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.8742 mL | 9.3712 mL | 18.7424 mL | 46.8560 mL |
| 5 mM | 0.3748 mL | 1.8742 mL | 3.7485 mL | 9.3712 mL | |
| 10 mM | 0.1874 mL | 0.9371 mL | 1.8742 mL | 4.6856 mL | |
| 15 mM | 0.1249 mL | 0.6247 mL | 1.2495 mL | 3.1237 mL | |
| 20 mM | 0.0937 mL | 0.4686 mL | 0.9371 mL | 2.3428 mL | |
| 25 mM | 0.0750 mL | 0.3748 mL | 0.7497 mL | 1.8742 mL | |
| 30 mM | 0.0625 mL | 0.3124 mL | 0.6247 mL | 1.5619 mL | |
| 40 mM | 0.0469 mL | 0.2343 mL | 0.4686 mL | 1.1714 mL | |
| 50 mM | 0.0375 mL | 0.1874 mL | 0.3748 mL | 0.9371 mL | |
| 60 mM | 0.0312 mL | 0.1562 mL | 0.3124 mL | 0.7809 mL | |
| 80 mM | 0.0234 mL | 0.1171 mL | 0.2343 mL | 0.5857 mL | |
| 100 mM | 0.0187 mL | 0.0937 mL | 0.1874 mL | 0.4686 mL |