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Referencia número: HY-10793

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CDK2-IN-56

CDK2-IN-56 (compound 39) is a pyrazoloquinazoline-3-carboxamide and CDK2/CyA inhibitor. CDK2-IN-56 can be used for the research of cancer.

Para uso exclusivo en investigación. No vendemos a pacientes.

No. CAS: 802536-13-6
Fòrmula: C₁₈H₂₅N₇O₃S
Peso molecular:419.50

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

CDK2-IN-56 Chemical Structure

No. CAS: 802536-13-6

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
- Descripciòn
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
Classifications
Bioz

Actividad biológica

Descripciòn

CDK2-IN-56 (compound 39) is a pyrazoloquinazoline-3-carboxamide and CDK2/CyA inhibitor. CDK2-IN-56 can be used for the research of cancer^[1].

IC₅₀ & Target

cdk2/cyclin A

Ver todos los productos específicos de isoformas CDK :

In Vitro

CDK2-IN-56 (Cpd39) potently inhibits CDK2/CyA with an actual pIC₅₀ of 8.699, and its activity is accurately predicted by both CoMFA and CoMSIA 3D-QSAR models^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

No. CAS 802536-13-6
Peso molecular 419.50
Fòrmula C₁₈H₂₅N₇O₃S
SMILES

O=C(NC)C1=NN(C)C2=C1CCC3=CN=C(NC4CCN(S(C)(=O)=O)CC4)N=C32
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Instrucciones de manejo (2659 KB)

Referencias

[1]. Lan P, et al. 3D-QSAR and docking studies on pyrazolo[4,3-h]qinazoline-3-carboxamides as cyclin-dependent kinase 2 (CDK2) inhibitors. Bioorg Med Chem Lett. 2010;20(22):6764-6772. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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