S-6123
S-6123 is a potent antimicrobial compound of the oxazolidinone series. S-6123 inhibits ribosomal protein synthesis without inhibiting DNA or RNA synthesis.
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- No. CAS: 87508-45-0
- Fòrmula: C10H12N2O5S
- Peso molecular:272.28
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Descripciòn
IC50 & Target
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Oxazolidinone |
In Vitro
S-6123 exhibits potent antimicrobial activity against gram-positive bacterias, Streptococcus pyogenes; Streptococcus agalactiae; Group C and G streptococci; Viridans group streptococci, penicillin susceptible; and Viridans group streptococci, penicillin resistant with MIC values of 16 μg/ml; 32 μg/ml; 16 μg/ml; 16 μg/ml; 8 μg/ml; 32 μg/ml, respectively.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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No. CAS 87508-45-0
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Peso molecular 272.28
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Fòrmula C10H12N2O5S
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SMILES
O=S(C1=CC=C(C=C1)N2C(O[C@H](C2)CO)=O)(N)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocolo
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Research Protocol for Infectious Diseases
Infectious-disease experiments test how pathogens interact with host barriers, innate immune receptors, inflammatory signaling, pathogen replication, and tissue injury; pattern-recognition receptors such as TLRs, RIG-I-like receptors, NOD-like receptors, and inflammasomes detect microbial molecules and activate NF-κB, interferon, and cytokine responses. The central hypothesis is that infection severity reflects the balance between pathogen burden and host response: protective inflammation restricts pathogen growth, whereas excessive or mislocalized inflammation contributes to tissue damage and disease phenotype. Unresolved questions include which host pathways are protective versus pathogenic, why some infection models fail to translate to human disease, and which combined readouts best predict clinically relevant infection outcomes.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)