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Cat. No.: HY-13631G

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Exatecan analog 13

Exatecan analog 13 is a analog of Exatecan (HY-13631). Exatecan (DX-8951) is a common toxin component in ADC preparation (ADC Cytotoxin) and an inhibitor of DNA topoisomerase I (IC₅₀ = 2.2 μM).

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CAS No.: 1599439-47-0
Formule: C₂₈H₂₉FN₄O₅
Masse moléculaire:520.55

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (275 KB)

Exatecan analog 13 Chemical Structure

CAS No.: 1599439-47-0

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Description

Exatecan analog 13 is a analog of Exatecan (HY-13631). Exatecan (DX-8951) is a common toxin component in ADC preparation (ADC Cytotoxin) and an inhibitor of DNA topoisomerase I (IC₅₀ = 2.2 μM)^[1].

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Chemical Information

CAS No. 1599439-47-0
Masse moléculaire 520.55
Formule C₂₈H₂₉FN₄O₅
SMILES

NCCCC(N[C@@H]1C2=C3C(C(N4C3)=CC([C@](O)(C(OC5)=O)CC)=C5C4=O)=NC6=CC(F)=C(C)C(CC1)=C62)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (275 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Mitsui I, et al. A new water-soluble camptothecin derivative, DX-8951f, exhibits potent antitumor activity against human tumors in vitro and in vivo. Jpn J Cancer Res. 1995 Aug;86(8):776-82. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Exatecan analog 13

Voir tous les produits spécifiques à Isoform ADC Payloads

Voir tous les produits spécifiques à Isoform Topoisomerase

Activité biologique

Description

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

Exatecan analog 13 Related Classifications

HY-13631G Related Classifications

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Keywords

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