EGLU
Based on 1 publication(s) in Google Scholar
EGLU ((2S)-α-Ethylglutamic acid; (2S)-α-EGLU) is a potent and competitive mGluR-2 receptor antagonist. EGLU interacts with (lS,3S)-ACPD-sensitive site with a Kd value of 66 μM. EGLU is an antidepressant agent.
For research use only. We do not sell to patients.
- Purity: 99.79%
- CAS No.: 170984-72-2
- Formula: C7H13NO4
- Molecular Weight:175.18
-
Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
Publications Citing Use of MedChemExpress (MCE) EGLU
More
Biological Activity
|
mGluR2 66 μM (Kd) |
EGLU (200 μM) selectively antagonizes (lS,3S)-ACPD-induced depressions of the monosynaptic component of the DRVRP, displaying little or no antagonist activity versus L-AP6 induced depressions or on the DRVRP alone[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 170984-72-2
-
Appearance Solid
-
Molecular Weight 175.18
-
Formula C7H13NO4
-
Color Off-white to light brown
-
SMILES
N[C@](CCC(O)=O)(CC)C(O)=O
-
Synonyms
(2S)-α-Ethylglutamic acid; (2S)-α-EGLU
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
-
Journal Impact Factor
-
Most Recent
Solvent & Solubility
H2O : 125 mg/mL (713.55 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (270 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 5.7084 mL | 28.5421 mL | 57.0841 mL | 142.7104 mL |
| 5 mM | 1.1417 mL | 5.7084 mL | 11.4168 mL | 28.5421 mL | |
| 10 mM | 0.5708 mL | 2.8542 mL | 5.7084 mL | 14.2710 mL | |
| 15 mM | 0.3806 mL | 1.9028 mL | 3.8056 mL | 9.5140 mL | |
| 20 mM | 0.2854 mL | 1.4271 mL | 2.8542 mL | 7.1355 mL | |
| 25 mM | 0.2283 mL | 1.1417 mL | 2.2834 mL | 5.7084 mL | |
| 30 mM | 0.1903 mL | 0.9514 mL | 1.9028 mL | 4.7570 mL | |
| 40 mM | 0.1427 mL | 0.7136 mL | 1.4271 mL | 3.5678 mL | |
| 50 mM | 0.1142 mL | 0.5708 mL | 1.1417 mL | 2.8542 mL | |
| 60 mM | 0.0951 mL | 0.4757 mL | 0.9514 mL | 2.3785 mL | |
| 80 mM | 0.0714 mL | 0.3568 mL | 0.7136 mL | 1.7839 mL | |
| 100 mM | 0.0571 mL | 0.2854 mL | 0.5708 mL | 1.4271 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
EGLU Related Classifications
HY-101332 Related Classifications
Powered by Bioz