TOP1288
TOP1288 is a narrow spectrum kinase inhibitor for P38α, Src and Syk kinase, with IC50 of 116nM, 24nM and 659nM, respectively. TOP1288 inhibits inflammatory cytokine release from inflamed biopsies and myofibroblasts.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 1630202-02-6
- Formule: C43H49N7O9S
- Masse moléculaire:839.96
-
Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Activité biologique
-
Chemical Information
- Pureté et documentation
-
Help & FAQs
Activité biologique
IC50: 24 nM (Src), 116 nM (P38α), 659 nM (Syk)
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
-
CAS No. 1630202-02-6
-
Masse moléculaire 839.96
-
Formule C43H49N7O9S
-
SMILES
O=C(NC1=CC(C(C)(C)C)=CC(NS(=O)(C)=O)=C1OC)NC2=CC=C(C3=C2C=CC=C3)OC4=NC(NC5=CC(C#C)=CC(C(NCCOCCOCCOC)=O)=C5)=NC=C4
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
TOP1288 Related Classifications
HY-160930 Related Classifications
Powered by Bioz