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Cat. No.: HY-164479

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GA001

GA001 is a potent G9a antagonist, with an IC₅₀ of 1.32 μM. GA001 induces autophagy and apoptosis that can be used for the breast cancer.

For research use only. We do not sell to patients.

CAS No.: 2097880-27-6
Formula: C₂₉H₂₄BrN₃O
Molecular Weight:510.42

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

GA001 Chemical Structure

CAS No.: 2097880-27-6

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

GA001 is a potent G9a antagonist, with an IC₅₀ of 1.32 μM. GA001 induces autophagy and apoptosis that can be used for the breast cancer^[1].

All Histone Methyltransferase Isoforms :

Chemical Information

CAS No. 2097880-27-6
Molecular Weight 510.42
Formula C₂₉H₂₄BrN₃O
SMILES

O=C(C1=CC(Br)=CC=C1)NC2=CC=C3C(N=C(N3CCCC4=CC=CC=C4)C5=CC=CC=C5)=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Zhang J, et al. Synthesis and biological evaluation of benzimidazole derivatives as the G9a Histone Methyltransferase inhibitors that induce autophagy and apoptosis of breast cancer cells. Bioorg Chem. 2017 Jun;72:168-181. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
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Chemical Information
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GA001

All Histone Methyltransferase Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

GA001 Related Classifications

HY-164479 Related Classifications