UBP 1112
UBP 1112 is a selective group III mGluR antagonist, with a Kd of 5.1 μM.UBP 1112 shows 96-fold affinity for group III over group II mGlu receptor (Kd, 488 μM), and shows no significant activity at group I mGlu receptor or iGlu receptor.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 339526-74-8
- Fòrmula: C10H14NO5P
- Peso molecular:259.20
-
Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Actividad biológica
-
Chemical Information
- Pureza y Documentación
- Referencias
-
Help & FAQs
Actividad biológica
Kd: 5.1 μM (group III mGluR), 488 μM (group II mGluR)[1]
UBP 1112 antagonises the depression of the fast component of the dorsal root-evoked ventral root potential induced by (S)-AP4 with apparent KD of 5.1 μM. UBP 1112 also antagonises the (S)-AP4 induced depression of synaptic transmission, with pA2 of 5.3. In addition, UBP 1112 (1 mM) displays little or no activity on (S)-3,5-DHPG-, NMDA-, AMPA- or kainate-induced responses on motoneurones[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
No. CAS 339526-74-8
-
Peso molecular 259.20
-
Fòrmula C10H14NO5P
-
SMILES
OC(C(N)(C1=CC(C)=C(P(O)(O)=O)C=C1)C)=O
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
UBP 1112 Related Classifications
HY-107517 Related Classifications
Powered by Bioz