A63162
A63162 is a specific 5-lipoxygenase (5-LOX) inhibitor. A63162 inhibits mitogen (PHA)-induced horse mononuclear cell (BMC) proliferation and inhibits Calcimycin (HY-N6687)-induced leukotriene LTB4 synthesis at the same concentration. A63162 can be used in the study of chronic obstructive pulmonary disease, arthritis and inflammatory bowel disease.
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- No. CAS: 111525-11-2
- Fòrmula: C17H19NO3
- Peso molecular:285.34
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
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Ver todos los productos específicos de isoformas Leukotriene Receptor
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Actividad biológica
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| RBL-1 | IC50 |
0.37 μM
Compound: 4b
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In vitro inhibition of 5-lipoxygenase in RBL-1 cells
In vitro inhibition of 5-lipoxygenase in RBL-1 cells
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[PMID: 3336029] |
Chemical Information
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No. CAS 111525-11-2
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Peso molecular 285.34
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Fòrmula C17H19NO3
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SMILES
CC(N(C(C)C1=CC=C(C=C1)OCC2=CC=CC=C2)O)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
A63162 Related Classifications
HY-118848 Related Classifications
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