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Referencia número: HY-136727A

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Ac-LEVD-CHO TFA

1 Cited Publications

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Based on 1 publication(s) in Google Scholar

Ac-LEVD-CHO (TFA) is an inhibitor of caspase-4. Ac-LEVD-CHO (TFA) can inhibit the expression and secretion of IL-1α expression as well as the activation of caspase-4 induced by the T. denticola periodontal pathogen surface protein Td92 in human gingival fibroblasts. Ac-LEVD-CHO (TFA) can also reduce the apoptosis due to the expression of the dominant negative adenoviral RNA-dependent protein kinase in A549 and PC3 cancer cell lines.

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Fòrmula: C₂₄H₃₇F₃N₄O₁₁
Peso molecular:614.57

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Please store the product under the recommended conditions in the Certificate of Analysis.

Ac-LEVD-CHO TFA Chemical Structure

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica

Descripciòn

Ver todos los productos específicos de isoformas Caspase :

Chemical Information

Peso molecular 614.57
Fòrmula C₂₄H₃₇F₃N₄O₁₁
Sequence

Ac-Leu-Glu-Val-Asp-CHO
Sequence Shortening

Ac-LEVD-CHO
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (1)

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PLoS Pathog

African swine fever virus pEP364R acts as an important inflammatory-inducing factor to activate NLRP3 inflammasome-mediated pyroptosis by regulating DDX3X. [Abstract]

2026 Feb 25;22(2):e1013874. PMID: 41739885

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Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Jun, H. K., et al., (2018). Caspase-4 activation by a bacterial surface protein is mediated by cathepsin G in human gingival fibroblasts. Cell death and differentiation, 25(2), 380–391. [Content Brief]

[2]. Pataer, A., et al., (2009). Inhibition of RNA-dependent protein kinase (PKR) leads to cancer cell death and increases chemosensitivity. Cancer biology & therapy, 8(3), 245–252. [Content Brief]

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1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Ac-LEVD-CHO TFA

1 Cited Publications

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Ac-LEVD-CHO TFA

Publications Citing Use of MedChemExpress (MCE) Ac-LEVD-CHO TFA

Ver todos los productos específicos de isoformas Caspase

Actividad biológica

Chemical Information

Publications (1)

Pureza y Documentación

Referencias

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Ac-LEVD-CHO TFA Related Classifications

HY-136727A Related Classifications