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Referencia número: HY-163804

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Cyprocide-B

Cyprocide-B is activated by Cytochrome P450 and converted to electrophilic metabolites that selectively kill nematodes C. elegans. Cyprocide-B is promising for research of selective nematicide.

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No. CAS: 49809-25-8
Fòrmula: C₁₀H₉ClN₂OS
Peso molecular:240.71

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

Cyprocide-B Chemical Structure

No. CAS: 49809-25-8

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
- Descripciòn
- In Vitro
- In Vivo
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
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Actividad biológica

Descripciòn

Cyprocide-B is activated by Cytochrome P450 and converted to electrophilic metabolites that selectively kill nematodes C. elegans. Cyprocide-B is promising for research of selective nematicide^[1].

Ver todos los productos específicos de isoformas Cytochrome P450 :

Ver todos los productos específicos de isoformas Parasite :

In Vitro

Cyprocide-B (50 µM, 3 days) is a selective nematicide with broad-spectrum activity in plant-parasitic nematodes (PPNs), and is safer for zebrafish than Tioxazafen (HY-136240)^[1].
Cyprocide-B (25 μM, 24 h) is bioactivated by CYP-35D1 to produce a reactive electrophile in C. elegans^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay^[1]

Cell Line:

Human cells, fungi, plant beneficial rhizobacteria
Concentration:

50 µM
Incubation Time:

3 days
Result:

Was relatively inactive against non-nematode phyla at the same concentration of killing nematodes in vitro.

In Vivo

Cyprocide-B (60 μM, 24 h) has potential utility in preventing root infestation by M. incognita in a soil environment^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

No. CAS 49809-25-8
Peso molecular 240.71
Fòrmula C₁₀H₉ClN₂OS
SMILES

CCSC1=NN=C(C2=CC=C(Cl)C=C2)O1
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Knox J, et al. Cyprocide selectively kills nematodes via cytochrome P450 bioactivation[J]. Nat Commun. 2024 Jul 2;15(1):5529. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Actividad biológica
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- In Vitro
- In Vivo
Chemical Information
Pureza y Documentación
Referencias

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Cyprocide-B

Ver todos los productos específicos de isoformas Cytochrome P450

Ver todos los productos específicos de isoformas Parasite