Desotamide
Desotamide is a cyclic hexapeptide antibiotic originally isolated from Streptomyces. It is active against S. aureus, S. pneumoniae, and methicillin-resistant S. epidermidis (MRSE; MICs=16, 12.5, and 32 μg/mL, respectively).
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- No. CAS: 194660-14-5
- Fòrmula: C35H52N8O7
- Peso molecular:696.84
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | IC50 |
>100 μM
Compound: 1
|
Cytotoxicity against human HepG2 cells after 72 hrs by SRB assay
Cytotoxicity against human HepG2 cells after 72 hrs by SRB assay
|
[PMID: 25072108] |
| MCF7 | IC50 |
>100 μM
Compound: 1
|
Cytotoxicity against human MCF7 cells after 72 hrs by SRB assay
Cytotoxicity against human MCF7 cells after 72 hrs by SRB assay
|
[PMID: 25072108] |
| NCI-H460 | IC50 |
>100 μM
Compound: 1
|
Cytotoxicity against human NCI-H460 after 72 hrs by SRB assay
Cytotoxicity against human NCI-H460 after 72 hrs by SRB assay
|
[PMID: 25072108] |
| SF-268 | IC50 |
>100 μM
Compound: 1
|
Cytotoxicity against human SF268 cells after 72 hrs by SRB assay
Cytotoxicity against human SF268 cells after 72 hrs by SRB assay
|
[PMID: 25072108] |
Chemical Information
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No. CAS 194660-14-5
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Peso molecular 696.84
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Fòrmula C35H52N8O7
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Synonyms
Desotamide A
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Sequence
cyclo(Asn-Gly-Trp-Leu-Leu-Ile)
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Sequence Shortening
cyclo(NGWLLI)
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)