DPP
Based on 1 Customer Validation
DPP is a Platinum(IV) complex, bearing pterostilbene-derived axial ligand. DPP inhibit the JAK2-STAT3 pathway in breast cancer (BC) cells with antiproliferative activity, and activates caspase-3 and cleaved poly ADP-ribose polymerase to induces apoptosis. DPP promotes the maturation and antigen presentation of dendritic cells, and exhibits in vivo safety.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza: 98.24%
- No. CAS: 2668267-47-6
- Fòrmula: C36H40Cl2N2O10Pt
- Peso molecular:926.70
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Almacenamiento:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Actividad biológica
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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No. CAS 2668267-47-6
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Appearance Solid
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Peso molecular 926.70
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Fòrmula C36H40Cl2N2O10Pt
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Color Light yellow to yellow
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SMILES
COC1=CC(OC)=CC(/C=C/C(C=C2)=CC=C2OCC([O-][Pt+4]([Cl-])([Cl-])([NH3])([NH3])[O-]C(COC(C=C3)=CC=C3/C=C/C4=CC(OC)=CC(OC)=C4)=O)=O)=C1
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Pureza y Documentación
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Ficha de datos (270 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)