Largazole thiol
Largazole thiol, the active form of Largazole (HY-13906), is a potent, selective and brain-penetrant class I HDAC inhibitor. Largazole thiol. Largazole thiol exerts antitumor and neuroprotective effects. Largazole thiol can be used for research of Glioblastoma.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 1132667-11-8
- Fòrmula: C21H28N4O4S3
- Peso molecular:496.67
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HCT-116 | IC50 |
5.9 nM
Compound: 2
|
Antiproliferative activity against human HCT116 cells after 48 hrs in absence of DTT by MTT assay
Antiproliferative activity against human HCT116 cells after 48 hrs in absence of DTT by MTT assay
|
[PMID: 25147612] |
Chemical Information
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No. CAS 1132667-11-8
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Peso molecular 496.67
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Fòrmula C21H28N4O4S3
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SMILES
C[C@@]12N=C(SC2)C3=CSC(CNC(C[C@H](OC([C@H](NC1=O)C(C)C)=O)/C=C/CCS)=O)=N3
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)