ZDLD13
ZDLD13, a β-carboline, is an orally active and selective CDK4/CycD3 inhibitor with an IC50 value of 0.38 μM. ZDLD13 exhibits potent anti-HCT116 activity including inhibition of colony formation, inhibition of invasion and migration, inducing of apoptosis, and arresting of G1 phase in cell cycle. ZDLD13 shows significant tumor growth inhibition in HCT116 tumor xenograft model.
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- No. CAS: 2762278-95-3
- Fòrmula: C18H14N4O
- Peso molecular:302.33
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
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CDK4/CycD3 0.38 μM (IC50) |
Chemical Information
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No. CAS 2762278-95-3
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Peso molecular 302.33
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Fòrmula C18H14N4O
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SMILES
O=C(C1=NC=CC2=C1NC3=C2C=CC=C3)NCC4=NC=CC=C4
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)