2. Gene
  3. DAP - death associated protein Gene

DAP - death associated protein Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as DAP1

Gene ID: 1611 | Gene type: protein coding

About DAP

Cytogenetic location: 5p15.2 Genomic coordinates (GRCh38): 5:10,679,230-10,761,234 (from NCBI)

This gene has 6 transcripts (splice variants), 167 orthologues and 1 paralogue. Ubiquitous expression in thyroid (RPKM 62.5), urinary bladder (RPKM 56.2) and 25 other tissues.

Summary

This gene encodes a basic, proline-rich, 15-kD protein. The protein acts as a positive mediator of programmed cell death that is induced by interferon-gamma. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]

DAP Products(2)

mRNA Protein Name
NM_001291963.2 NP_001278892.1 death-associated protein 1 isoform 1
NM_004394.3 NP_004385.1 death-associated protein 1 isoform 2

DAP Protein Structure

DAP

DAP: Death-associated protein (12 - 102)

  • 0
  • 102 a.a.
Protein Preferred Names Protein Names

death-associated protein 1

DAP-1

Related Diseases

Diseases Alias
Alpha-Thalassemia

Alpha Thalassemia

Alpha Thalassaemia

Alpha Plus Thalassemia

Thalassemia, Alpha-

Thalassemias, Alpha-

A-Thalassemia

Α-Thalassemia

A-THAL

Thalassemia

Alpha Thalassaemia Syndrome
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (41)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-100714A D-AP5 Antagonist 99.81% Unkown
HY-33046 N-Boc-dolaproine 99.94% Unkown
HY-78931 Boc-Dap-NE 99.92% Unkown
HY-P1070 Amylin, amide, human 98.46% Unkown
HY-P4931 Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 99.87% Unkown
HY-W010962 Fmoc-Dap(Alloc)-OH 99.59% Unkown
HY-78932A Dap-NE hydrochloride 99.98% Unkown
HY-P3474A Mca-Pro-Leu-Gly-Leu-Dap-Ala-Arg-NH2 TFA 99.39% Unkown
HY-130961 Boc-Val-Dil-Dap-OH 98.52% Unkown
HY-78931A (R,S,S,R,S)-Boc-Dap-NE / Unkown
HY-P3120 Mca-Pro-Leu-Ala-Cys(Mob)-Trp-Ala-Arg-Dap(Dnp)-NH2 / Unkown
HY-W008325 Boc-L-Dap-OH ≥97.0% Unkown
HY-78931B (S,S,S,S,R)-Boc-Dap-NE / Unkown
HY-78931C (S,S,R,S,R)-Boc-Dap-NE / Unkown
HY-78931E (R,S,R,S,R)-Boc-Dap-NE / Unkown
HY-78931F (R,S,S,S,R)-Boc-Dap-NE / Unkown
HY-78931G Boc-Dap-NE (GMP) / Unkown
HY-100714B L-AP5 Antagonist / Unkown
HY-130956 Boc-NMe-Val-Val-Dil-Dap-OH / Unkown
HY-130975 Boc-Val-Dil-Dap-Phe-OMe / Unkown
HY-130976 N-Boc-Val-Dil-Dap-Doe / Unkown
HY-143700 18:0 DAP / Unkown
HY-144020 14:0 DAP / Unkown
HY-144022 16:0 DAP / Unkown
HY-151640 Fmoc-DAP-N3 / Unkown
HY-P1070A Amylin, amide, human TFA / Unkown
HY-P3098 Mca-P-Cha-G-Nva-HA-Dap(DNP)-NH2 / Unkown
HY-P3474 Mca-Pro-Leu-Gly-Leu-Dap-Ala-Arg-NH2 / Unkown
HY-P3477 Mca-PLA-Nva-Dap(Dnp)-AR-NH2 / Unkown
HY-P5383 Mca-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 / Unkown
HY-RS03525 DAP Human Pre-designed siRNA Set A / Unkown
HY-RS03526 DAP3 Human Pre-designed siRNA Set A / Unkown
HY-151715 N3-D-Dap(Fmoc)-OH / Unkown
HY-151736 N3-L-Dap(Boc)-OH / Unkown
HY-151780 Fmoc-L-Dap(Pentynoyl)-OH / Unkown
HY-151781 Fmoc-L-Dap(Poc)-OH / Unkown
HY-151849 Z-L-Dap(N3)-OH / Unkown
HY-78932 Dap-NE / Unkown
HY-78932C (2S,3R)-Dap-NE hydrochloride / Unkown
HY-78932D (2R,3R)-Dap-NE hydrochloride / Unkown
HY-100781 D-AP4 / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus DAP RGD RGD:620641
Bos taurus DAP VGNC VGNC:50122
Macaca mulatta DAP VGNC VGNC:71730
Mus musculus DAP MGD MGI:1918190
Others DAP NCBI