Malt1 - MALT1 paracaspase Gene

Predicted to enable several functions, including identical protein binding activity; protease binding activity; and protein self-association. Predicted to contribute to kinase activator activity. Predicted to be involved in several processes, including lipopolysaccharide-mediated signaling pathway; positive regulation of immune response; and positive regulation of macromolecule metabolic process. Predicted to act upstream of or within several processes, including B-1 B cell differentiation; cellular response to lipopolysaccharide; and regulation of T cell receptor signaling pathway. Predicted to be located in cytosol and fibrillar center. Predicted to be part of CBM complex and polkadots. Human ortholog(s) of this gene implicated in immunodeficiency 12; lymphoma; and non-Hodgkin lymphoma. Orthologous to human MALT1 (MALT1 paracaspase). [provided by Alliance of Genome Resources, Apr 2022]