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55731

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14

Inhibitors & Agonists

1

Inhibitory Antibodies

4

Antibodies

8

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-109080
    Belvarafenib
    5 Publications Verification

    HM95573; GDC-5573; RG6185

    		 Raf Cancer
    Belvarafenib (HM95573) is a potent and pan RAF (Rapidly Accelerated Fibrosarcoma) inhibitor, with IC50s of 56 nM, 7 nM and 5 nM for B-RAF, B-RAF v600E and C-RAF respectively .
    Belvarafenib
  • HY-146413
    HF50731

    		CXCR HIV Infection Cancer
    HF50731 (compound 21) is a potent CXCR4 antagonist. HF50731 shows strong CXCR4 binding affinity, with IC50 of 19.8 nM. HF50731 effectively inhibits calcium mobilization, cell migration, and HIV-1 infection via CXCR4 coreceptor, with IC50 values of 119.2 nM, 621.4 nM and 1.5 μM .
    HF50731
  • HY-U00010
    Dazopride

    AHR-5531

    		 Others Metabolic Disease
    Dazopride is an antiemetic agent.
    Dazopride
  • HY-RI01721
    hsa-miR-5571-3p inhibitor

    		MicroRNA Cancer
    hsa-miR-5571-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
    hsa-miR-5571-3p inhibitor
    hsa-miR-5571-3p inhibitor
  • HY-R01722A
    hsa-miR-5571-5p agomir

    		MicroRNA Cancer
    hsa-miR-5571-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    hsa-miR-5571-5p agomir
    hsa-miR-5571-5p agomir
  • HY-R01721
    hsa-miR-5571-3p mimic

    		MicroRNA Cancer
    hsa-miR-5571-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.
    hsa-miR-5571-3p mimic
    hsa-miR-5571-3p mimic
  • HY-R01722
    hsa-miR-5571-5p mimic

    		MicroRNA Cancer
    hsa-miR-5571-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.
    hsa-miR-5571-5p mimic
    hsa-miR-5571-5p mimic
  • HY-109080A
    Belvarafenib TFA

    HM95573 TFA; GDC-5573 TFA; RG6185 TFA

    		 Raf Cancer
    Belvarafenib TFA (HM95573 TFA) is a potent and pan RAF (Rapidly Accelerated Fibrosarcoma) inhibitor, with IC50s of 56 nM, 7 nM and 5 nM for B-RAF, B-RAFv 600E and C-RAF respectively .
    Belvarafenib TFA
  • HY-157961
    E-5531

    		Toll-like Receptor (TLR) Inflammation/Immunology
    E-5531 is an endotoxin antagonist. E-5531 quickly becomes inactive after binding with HDL. E-5531 can block the Toll like receptor 4 (TLR4) signaling pathway. E-5531 can be used for the study of endotoxemia and septic shock .
    E-5531
  • HY-P992347
    DS-5573a

    DS-5573a
  • HY-R01721A
    hsa-miR-5571-3p agomir

    		MicroRNA Cancer
    hsa-miR-5571-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    hsa-miR-5571-3p agomir
    hsa-miR-5571-3p agomir
  • HY-RI01722
    hsa-miR-5571-5p inhibitor

    		MicroRNA Cancer
    hsa-miR-5571-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
    hsa-miR-5571-5p inhibitor
    hsa-miR-5571-5p inhibitor
  • HY-RI01722A
    hsa-miR-5571-5p antagomir

    		MicroRNA Cancer
    hsa-miR-5571-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    hsa-miR-5571-5p antagomir
    hsa-miR-5571-5p antagomir
  • HY-RI01721A
    hsa-miR-5571-3p antagomir

    		MicroRNA Cancer
    hsa-miR-5571-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    hsa-miR-5571-3p antagomir
    hsa-miR-5571-3p antagomir

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