HLDA-221
Based on 1 Customer Validation
HLDA-221 is a non-covalent regulated induced proximity targeting chimeras (RIPTAC). The binding of HLDA-221 to BRD4-BD1 is significantly increased after pre-incubation with FKBP. HLDA-221 can be used in cancer research.
For research use only. We do not sell to patients.
- Purity: 99.24%
- CAS No.: 3077339-82-0
- Formula: C64H78ClN7O13S
- Molecular Weight:1220.86
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Storage:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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BRD4 (BD1) |
Chemical Information
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CAS No. 3077339-82-0
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Appearance Solid
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Molecular Weight 1220.86
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Formula C64H78ClN7O13S
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Color White to off-white
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SMILES
CC(C(C(C(C=C1)=CC=C1Cl)=N[C@H]2CC(NCCOCCOCCN(C(COC3=CC=CC([C@@H](CCC4=CC(OC)=C(OC)C=C4)OC([C@@H]5CCCCN5C([C@H](C6=CC(OC)=C(OC)C(OC)=C6)CC)=O)=O)=C3)=O)C)=O)=C(S7)N8C2=NN=C8C)=C7C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvent & Solubility
DMSO : ≥ 100 mg/mL (81.91 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.8191 mL | 4.0955 mL | 8.1909 mL | 20.4774 mL |
| 5 mM | 0.1638 mL | 0.8191 mL | 1.6382 mL | 4.0955 mL | |
| 10 mM | 0.0819 mL | 0.4095 mL | 0.8191 mL | 2.0477 mL | |
| 15 mM | 0.0546 mL | 0.2730 mL | 0.5461 mL | 1.3652 mL | |
| 20 mM | 0.0410 mL | 0.2048 mL | 0.4095 mL | 1.0239 mL | |
| 25 mM | 0.0328 mL | 0.1638 mL | 0.3276 mL | 0.8191 mL | |
| 30 mM | 0.0273 mL | 0.1365 mL | 0.2730 mL | 0.6826 mL | |
| 40 mM | 0.0205 mL | 0.1024 mL | 0.2048 mL | 0.5119 mL | |
| 50 mM | 0.0164 mL | 0.0819 mL | 0.1638 mL | 0.4095 mL | |
| 60 mM | 0.0137 mL | 0.0683 mL | 0.1365 mL | 0.3413 mL | |
| 80 mM | 0.0102 mL | 0.0512 mL | 0.1024 mL | 0.2560 mL |
HLDA-221 Related Classifications
HY-156820 Related Classifications
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