Hsp90-IN-40
Hsp90-IN-40 (Compound 15b) is a heat shock protein 90 (Hsp90) C-terminal inhibitor. Hsp90-IN-40 exhibits antiproliferative activity against SKBr3 and MCF-7 breast cancer cells (IC50 of 2.57 µM and 2.43 µM, respectively). Hsp90-IN-40 inhibits cancer cell growth by inhibiting the Hsp90 C-terminal function, leading to Hsp90-dependent protein degradation. Hsp90-IN-40 can be used in breast cancer research.
For research use only. We do not sell to patients.
- CAS No.: 2169278-81-1
- Formula: C33H40N2O4
- Molecular Weight:528.68
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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HSP90 |
Chemical Information
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CAS No. 2169278-81-1
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Molecular Weight 528.68
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Formula C33H40N2O4
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SMILES
COC1=C(C2=CC(OC)=CC=C2)C=C(C=C1)C(N[C@@H]3CC[C@H](C4=CC=C(C=C4)OC5CCN(CC5)C)CC3)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)